Chads vasc score calculator

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Calculate CHADS-VASc Score and evaluate indication for anticoagulation Last Updated: . CHA2DS2-VASc Score Calculator Congestive Heart Failure

Calculate CHADS-VASc Score and evaluate

And protected LMCA (patients with a history of previous CABG). Further calculations were performed based on the severity of CAD. Patients were divided into four subgroups: isolated LMCA narrowing, with additional 1-, 2- or 3-vessel disease (1-VD, 2-VD, 3-VD, respectively). The design of the study is very well conceived.In the overall cohort, EuroSCORE II as compared to ACEF and CHA2DS2-VASc, provided the best discriminative performance for the 30-day mortality (P=0.03 and PIn patients with unprotected LMCA, EuroSCORE II showed better discriminative performance than ACEF and CHA2DS2-VASc in short-term (P=0.051 and PPertinent conclusions.Reply: We thank for the kind words and remark regarding recent guidelines recommendations to use CHA2DS2-VA instead of CHA2DS2-VASc. To make our analysis up to date, we have now included CHADS-VA analyses in the manuscript. However, to remain maximal generalizability, we decided not to remove results investigating validation of CHA2DS2-VASc score – calculator widely used for the past 14 years.Now, readers can find information on the performance of four calculators in present manuscript.Changes: Please see changes in the Introduction, Methods, Results and Discussion section and new Figure 3 now included in the manuscript. Reviewer 3 Report Comments and Suggestions for AuthorsIn the study the authors established that EuroSCORE II showed good mortality prediction the short-term observation, its predicted risk should be interpreted with caution due to poor calibration. ACEF score and EuroSCORE II may be useful in long-term mortality prediction.Although the findings are impressive and practically useful, I would like to make some comments.1. The authors might discuss the patients-related factors incorporated into the EuroSCORE II, which had not been added to Table 1.2. ACEF score was developed for 30-day mortality after elective or emergency cardiac surgery, so it is not suitable for the long-term risk evaluation. Please, explaine this.3. CHA₂DS₂-VASc Score is avaiable for Atrial Fibrillation Stroke Risk,

Calculate CHADS-VASc Score and evaluate indication for

Compared to ACEF and CHA2DS2-VASc, provided the best discriminative performance for the 30-day mortality (P=0.03 and PIn patients with unprotected LMCA, EuroSCORE II showed better discriminative performance than ACEF and CHA2DS2-VASc in short-term (P=0.051 and P in the long-term EuroSCORE II and ACEF were better than CHA2DS2-VASc (P both two model comparisons). In the subgroup of post-CABG patients, EuroSCORE II and ACEF provided moderate 30-day mortality discriminative performance, as opposed to poor CHA2DS2-VASc discrimination. In the long-term, all of the analysed CPMs provided acceptable discriminative performance.Pertinent conclusions. Author Response The study presents actual data with a lot of clinical implications.The present study analyses data collected retrospectively from the BIA-LM Registry.In brief, the registry is a single-centre database of LMCA PCI performed in the Department of Invasive Cardiology, Medical University of Bialystok, Poland analyzing patients referred for surgical or conservative treatment during a period of 4 years, from 12.27.2008 to 02.21.2022.A final cohort of 851 individuals undergoing LMCA angioplasty were included into analysis. All analysed scores were recalculated for every patient enrolled in the study: EuroSCORE II using the interactive calculator (available at CHA2DS2-VASc as sum of 1 point for diagnosis of heart failure, hypertension, age between 65-74 years, diabetes mellitus, vascular disease, female gender and 2 points for age ≥75 years and prior stroke or transient ischemic attack, and ACEF as age divided by ejection fraction plus one if serum creatinine was ≥2 mg/dl.One mention I have concerning CHA2DS2-VASC Score. Since 30 august 2024 is not actual. After 2024ESC Guideline for atrial fibrillation, CHA2DS2-VA Score is used instead of CHA2DS2-VASc. = Congestive heart failure, hypertension, age ≥75 years (2 points), diabetes mellitus, prior stroke/transient ischaemic attack/arterial thromboembolism (2 points), vascular disease, age 65–74 years (score)Analyses were performed for the overall population, patients with unprotected LMCA (i.e., with no previous CABG)

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Risk evaluation. Please, explaine this.Reply 2: Thank you for the comment. Indeed, ACEF Score developed by Ranucci was initially used for in-hospital and 30-day after elective cardiac surgery moratlity prediction. It’s performance in this setting was validated multiple times before. Thus, the aim of our study was to seek for novel application of the well-known clinical prediction models.We investigated both short- and long-term prognostic value in patients undergoing PCI for significant LMCA stenosis. In the short-term, ACEF provided worse mortality prediction than EuroSCORE II, however, in the long-term observation ACEF showed the best discriminative performance amongst analysed calculators. Good long-term performance of ACEF score suggests that universal three factors may act as a surrogate for comorbidity burden and general health status. This may have clinical implications, as patients with higher ACEF scores may obtain more personalized post-procedure surveillance. Higher-risk patients can be identified for closer monitoring, targeted follow-up, and intensive secondary and tertiary prevention, such as intensification of guideline-directed medical therapy targeted at nephroprotection and heart failure with mildly reduced or reduced ejection fraction – treatment including ACE inhibitors, SLGT-2 inhibitors, and finerenone in selected individuals.Changes 2: Please see Discussion section modified.CHA₂DS₂-VASc Score is avaiable for Atrial Fibrillation Stroke Risk, so that is not corresponded to the aim of the study.Reply 3: Thank you for this comment, we are glad to clarify this issue. In fact, none of the three analysed calculators were initially developed for assessment of adverse cardiovascular events in patients undergoing coronary angioplasty. A number of CPMs were developed in order to facilitate decision-making in patients with coronary artery disease undergoing PCI, including anatomic SYNTAX, Mayo Clinic and NCDR or, combining anatomic conditions with clinical data SYNTAX II. However, the inclusion of many variables leading to higher accuracy at the expense of complexity and less bedside usefulness. Calculate CHADS-VASc Score and evaluate indication for anticoagulation Last Updated: . CHA2DS2-VASc Score Calculator Congestive Heart Failure Calculate CHADS-VASc Score and evaluate indication for anticoagulation Last Updated: CHA2DS2-VASc Score Calculator Congestive Heart Failure

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Colon. Reply: We thank for the time and effort invested in reviewing our manuscript. We have changed the title accordingly.Changes: Please see modified title of the paper. Reviewer 2 Report Comments and Suggestions for AuthorsThe study presents actual data with a lot of clinical implications.The present study analyses data collected retrospectively from the BIA-LM Registry.In brief, the registry is a single-centre database of LMCA PCI performed in the Department of Invasive Cardiology, Medical University of Bialystok, Poland analyzing patients referred for surgical or conservative treatment during a period of 4 years, from 12.27.2008 to 02.21.2022.A final cohort of 851 individuals undergoing LMCA angioplasty were included into analysis. All analysed scores were recalculated for every patient enrolled in the study: EuroSCORE II using the interactive calculator (available at CHA2DS2-VASc as sum of 1 point for diagnosis of heart failure, hypertension, age between 65-74 years, diabetes mellitus, vascular disease, female gender and 2 points for age ≥75 years and prior stroke or transient ischemic attack, and ACEF as age divided by ejection fraction plus one if serum creatinine was ≥2 mg/dl.One mention I have concerning CHA2DS2-VASC Score. Since 30 august 2024 is not actual. After 2024ESC Guideline for atrial fibrillation, CHA2DS2-VA Score is used instead of CHA2DS2-VASc. = Congestive heart failure, hypertension, age ≥75 years (2 points), diabetes mellitus, prior stroke/transient ischaemic attack/arterial thromboembolism (2 points), vascular disease, age 65–74 years (score)Analyses were performed for the overall population, patients with unprotected LMCA (i.e., with no previous CABG) and protected LMCA (patients with a history of previous CABG). Further calculations were performed based on the severity of CAD. Patients were divided into four subgroups: isolated LMCA narrowing, with additional 1-, 2- or 3-vessel disease (1-VD, 2-VD, 3-VD, respectively). The design of the study is very well conceived.In the overall cohort, EuroSCORE II as

CHADS-VASc Score as a Predictor of No- Reflow

So that is not corresponded to the aim of the study.4. The authors should explaine how many patients with AF were included in the analysis and why they used CHA₂DS₂-VASc Score for the evaluation of clinical outcomes after PCI.5. Please, extend the section Discussion and Conclusio taking into consideration the issues mentioned above. Author Response In the study the authors established that EuroSCORE II showed good mortality prediction the short-term observation, its predicted risk should be interpreted with caution due to poor calibration. ACEF score and EuroSCORE II may be useful in long-term mortality prediction.Although the findings are impressive and practically useful, I would like to make some comments.The authors might discuss the patients-related factors incorporated into the EuroSCORE II, which had not been added to Table 1.Reply 1: Thank you for this important suggestion.In our dataset we gathered all of the variables initially included in EuroSCORE II calculator. Actually, most of the variables incorporated into the EuroSCORE II are already included in Table 1., although some of them are not directly titled as in the original publication by Nashef et al. [1], e.g., patients with severe valvular disease were considered either 2- or more procedures, patients with STEMI were considered emergency procedure. Due to the low prevalence of selected variables, some of them were not included in the Table 1., however, now as the Reviewer has suggested, we have updated Table 1. with new selected data included in EuroSCORE II calculator.[1] Samer A.M. Nashef, François Roques, Linda D. Sharples, Johan Nilsson, Christopher Smith, Antony R. Goldstone, Ulf Lockowandt, EuroSCORE II, European Journal of Cardio-Thoracic Surgery, Volume 41, Issue 4, April 2012, Pages 734–745, 1: Please see Table 1. updated.ACEF score was developed for 30-day mortality after elective or emergency cardiac surgery, so it is not suitable for the long-term

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Imaging (EACVI) [6]. The anticoagulation protocol during emergency department rhythm control relied on standard operation procedure (SOP) implemented within the ED but remained at the discretion of the attending physician. SOPs for anticoagulation protocol strictly followed guidelines of the ESC in their latest version at the time of presentation. Briefly patients with a CHA2DS2-VASC Score of ≥ 2 in men and ≥ 3 in women recieved anticoagulation. Patients with a score below the cut off recieved anticoagulation, if a cardioversion was planned and for 4 weeks after cardioversion. Thereafter anticoagulation was decided by the treating physician.Patients undergoing emergency PCI recieved appropriate antiplatelet treatment (aspirin, clopidogrel) other potent antiplatelet agents (prasugrel, ticagrelor) were only administered in the cathlab. In general OAC was administered as soon as possible.Unless appropriate anticoagulation was documented or the onset of AF was unequivocally recent, a transesophageal echocardiogram for exclusion of intracardiac thrombus was performed prior to cardioversion. The only exception was emergency cardioversion which could not be delayed.Statistical analysisContinuous variables were tested for normal distribution using the Kolmogorov–Smirnov test. Normally distributed data is presented as means (standard deviations, SD). Non-normally distributed data is presented as medians (25th, 75th percentiles, IQR). Kaplan–Meier estimates are shown as counts or percentages. Here, groups were compared with the log-rank test. For categorical variables groups were compared using chi-squared test or Fisher’s exact test. For continuous variables, unpaired Student’s t-test or Wilcoxon rank-sum test was used. A multivariate Cox proportional hazards regression was performed to determine predictors for outcome parameters. The

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Limits the clinical utility.Thus, we included three, arguably most commonly used cardiovascular clinical prediction models. We found that EuroSCORE II and ACEF may be especially useful in short- and long-term mortality prediction. When it comes to CHA2DS2-VASc, its discriminative performance was inferior to the aforementioned calculators. However, it showed good calibration in most of the subgroups suggesting that it’s thromboembolic risk score, actually indicating co-morbidity burden severity, may be useful when assessing low- or high adverse event risk patients, especially on the populational level.Changes 3: Please see Discussion section modified.The authors should explaine how many patients with AF were included in the analysis and why they used CHA₂DS₂-VASc Score for the evaluation of clinical outcomes after PCI.Reply 4: Thank you for this comment. The data for rates of concomitant atrial fibrillation are provided in Table 1. As we elaborated above, we included three widely adopted risk scores and sought to analyse their performance in short- and long-term mortality prediction amongst patients undergoing left main coronary artery PCI.The models were validated in various clinical settings outside of their initial purpose, however, whether these risk scores may have short- and long-term prognostic value in patients undergoing PCI for significant LMCA stenosis remains to be unknown. Thus, aiming the gap in evidence, the purpose of study was to assess relation between EuroSCORE II, CHA2DS2-VASc, ACEF and mortality in the overall population of patients undergoing LMCA angioplasty. Moreover, our analyses included stratification on the severity and extent of CAD, and based on the history of previous revascularization.Changes 4: Please see Discussion section modified.Please, extend the section Discussion and Conclusio taking into consideration the issues mentioned above.Reply 5: Thank you for the valuable comments. As suggested, we have addressed them in the discussion section.Changes 5: Please see Discussion section modified accordingly. Round 2 Reviewer 3. Calculate CHADS-VASc Score and evaluate indication for anticoagulation Last Updated: . CHA2DS2-VASc Score Calculator Congestive Heart Failure Calculate CHADS-VASc Score and evaluate indication for anticoagulation Last Updated: CHA2DS2-VASc Score Calculator Congestive Heart Failure

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Nastiness and purely petty actions of the semi-fleshed out characters, but it needs so much more! Little Secrets is just that, little secrets, but it should be so much more! I want Colossal Life-Ruining Secrets! Playing With Fire is just a teaser and I am hoping book 2 is a lot more.March 9, 2009As Alison watches her grandmother walk into the pool house and as her grandmother is in the pool house it goes into flames. As Alison watches the burning pool house she’s hoping her grandmother is alright. This is the ending of the little secrets 1written by Emily Blake. Determining that this ending was effective is by not knowing what happened to Alison’s grandmother. The character that was most opinionated about others is Tom. Tom is Chads best friend and Alison is Chads ex but Kelly is Chads girlfriend now. Tom is mad at Chad cause he thinks he’s always doing his homework and Tom thinks Chad doesn’t deserve Kelly since he’s has been in love with Kelly since forever, and tom thinks Zoey his twin sister is an idiot. The piece of information that I found most interesting is about the Diamonds family. Alison’s grandmother is the cause for her mother being in jail. Four words or phrases that would best describe this book with explanations on every thing that happens. One word is suffering because many people suffer in this book. Second word is suspenseful events on not knowing what’s going to happen next. Third word is wound’s ones feelings since many people get hurt in the book. The forth word is false face cause everybody is hiding what they are really feeling inside and pretending to act like someone else there not like they are wearing a mask4 reviewsDecember 14, 2008Little Secrets-Playing with fire is

Calculate CHADS-VASc Score and evaluate

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Calculate CHADS-VASc Score and evaluate indication for

Hey there, young warriors! Let’s dive into the amazing world of the USMC (United States Marine Corps) Physical Fitness Test (PFT) and Combat Fitness Test (CFT) Calculators. These awesome tools are here to help you assess and measure your physical readiness for the Marine Corps adventures ahead!To make things even easier, here’s the USMC PFT/CFT Calculator:USMC PFT/CFT CalculatorUSMC PFT CalculatorCFT CalculatorMovement to ContactManeuver Under FireAmmo Can LiftsResultsPFT Calculator ExplainedCFT Calculator ExplainedRelated Posts USMC PFT Calculator Here you can calculate your PFT score and check your fitness level for the Marine Corps Physical Fitness Test. Enter your details and performance metrics to see your score, including push-ups, pull-ups, crunches, and running/rowing events. Gender: Age: Pushups/Pullups: Crunches: Event: Time (mm:ss): Pushups/Pullups: Points Crunches: Points Running/Rowing: Points Total PFT Score: Class: CFT Calculator Get ready to test your combat fitness with the CFT Calculator! It helps you assess your readiness for combat-related activities. Measure your speed, agility, and upper body strength in different sections like Movement to Contact, Maneuver Under Fire, and Ammo Can Lifts. Movement to Contact Time (mm:ss): Altitude: Maneuver Under Fire Time (mm:ss): Altitude: Ammo Can Lifts Number of Lifts: 84 Results MTC: points ACL: points MANUF: points Total CFT Score: Class: If you’re looking for an accurate and efficient USMC PFT/CFT Calculator, look no further! Enter your data into the calculator to accurately calculate your Physical Fitness Test or Combat Fitness Test scores. The calculator is precise and convenient to use, making it an excellent tool for assessing your readiness.PFT Calculator ExplainedThe USMC PFT Calculator is a tool used to measure your physical fitness. It uses a specific formula to calculate your PFT score, which is based on how well you perform in different fitness activities. Let’s break it down:Pushups/Pullups: This measures your upper body strength. The more pushups or pullups you can do, the higher your score. The table below shows how many points you can earn based on the number of repetitions:RepetitionsPoints0015210315……20+100Crunches: This tests your abdominal strength. The more crunches you can do, the higher your score. The table below shows how many points you can earn